and pharmacological properties of Kigelia africana (Lam.) Balmkheera, Isopinnatal, Kigelin, Chemical constituents, Medicinal properties. Objective: Kigelia africana, a tropical tree, which has long been used in African . Analytical grade solvents (Fischer chemicals) were used for isolation and. cancer with drugs (pharmacotherapy) or with chemical compounds ( chemotherapy) in family comprises 21 species, of which Kigelia africana. (Lam. ) Benth is.

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Comprehensive scientific demystification of Kigelia africana: The phytochemical components of Kigelia pinnata based on the preliminary extract screening. The africaa extract exhibited substantial antileishmanial activity of Leishmania donovani. Solvents were re-distilled before use. Stender S, Dyerberg J. Prostaglandins Leukot Essent Fatty Acids. It could serve as intermediates in the manufacture of a variety of food ingredients. Effects of some medicinal plants on the oxidative defense system.

Antioxidant activity measured in different solvent fractions obtained from Mentha spicata Linn.: The compound was later obtained as a white precipitate from the oil mixture. Total phenolic content and reducing power potentials of the extract The total phenolic content was cheicals found to be higher in KPRE at 0. Nat Prod Res ; Stuppner H, Wagner H.

Special attention may have to be paid to the extraction method. Activity of extracts of Kigelia pinnata against melanoma and renal kigeliw cell lines.

Isolation and structure of two new dihydroisocoumarins from Kigelia pinnata. Support Center Support Center. The antioxidant activity which correlated with agricana total phenolic content of the extracts was assumed to be from the total phenolic content of the extracts. Medicinal herbs in Malawi and their uses. Iridoids from Kigelia pinnata DC.


It is believed that the presence of ROS is essential in cells as they can act as key signaling molecules for the activation of the stress-responses and defense pathways Halliwell, kogelia 19 ]; Foyer and Noctor, [ 17 ]. Wherever, the tree grows it is usually evergreen especially chemifals places where rainfall occurs throughout the year, but deciduous in places of long dry season. The leaves of K. The methanol-extract was decanted, filtered and concentrated in vacuo to yield The structures of the Compounds isolated from K.

Adeosun1 and Gabriel A. How to cite this article: It is the only unsaturated free fatty acid with a Adeyemi1 Essiet Akpan1 Charles B.

New Constituents of Kigelia pinnata Leaves – SciAlert Responsive Version

The absorbance at nm was monitored in presence of different concentrations of extracts. Activity of extracts and naphthoquinones from Kigelia pinnata against Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense. An analysis by ABTS decolorization assay.

Acetaminophen-induced liver damage chemicalz mice: Spectrum Books Ltd; Analysis of tocopherols by capillary supercritical fluid chromatography and mass spectrometry.

Bioactive compounds in nutrition and health-research methodologies for establishing biological function: A procedure to measure the antiradical efficiency of polyphenols. You are free to copy, distribute and transmit the work, provided the original author and source are credited. The phytochemical analysis conducted on the K.

Conclusions Kigelia pinnata root is rich in phytochemicals with proven antioxidant activities. Higher absorbance of the reaction mixture indicates higher reductive potential. The dose dependent trend observed for the KPRH could be as a result of synergistic free radical scavenging ability of compounds in the oil which apparently dampens the effect of the erucic acid.


The plant root was selected for the study because of the reported phytochemicals which include iridoids, naphthoquinones and coumarins among others.

Chemical composition and antioxidant potentials of Kigelia pinnata root oil and extracts

The mixture containing 2. Iridoids and iridoid glucosides from fruits of Crescentia cujete. The radical was protected from light. The structures of phenolic compounds which exhibited antioxidant activity in the ethyl acetate fraction would need to be elucidated.

Essential oil analysis and antimicrobial activity of eight Stachys species from Greece. Screening of 70 medicinal plant extracts for antioxidant capacity and total phenols. The relative percentages of the identified compounds are listed in Table 1. The methanol extract together with the isolated compounds were tested for chemucals bioactivities in a series of cell-based assays.

Chemical composition and antioxidant potentials of Kigelia pinnata root oil and extracts

Antioxidant and antimicrobial activity of cuticular wax from Kigelia africana. Trans fatty acids in hydrogenated fat inhibited africsna synthesis of the polyunsaturated fatty acids in the phospholipid of arterial cbemicals. In humans, the plant polyphenols consumed through the diet are considered as effective protective agents against the ROS, which are known to be involved in the pathogenesis of aging and many degenerative diseases such as cardiovascular diseases and cancers Virgili and Scaccini, [ 51 ]; Kris-Etherton et al.